Virtual Touch Reference Values - Society of Radiologists in Ultrasound Values

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Virtual Touch Reference Values Absent or mild fibrosis Significant fibrosis Severe fibrosis Cirrhosis Metavir Score F0–F1 F2 F3 F4 10543 0421 · ©Siemens Medical Solutions USA, Inc., 2021 Siemens Healthineers 1.2 m/s 1.3 m/s 1.5 m/s 1.7 m/s values† 4 kPa 5 kPa 7 kPa 9 kPa 1.3 m/s 1.7 m/s 2.1 m/s Society of Radiologists in Ultrasound (SRU)†† Not applicable < 9 kPa rules out cACLD in the < 5 kPa Likely Normal absence of other clinical signs > 13 kPa rules in cACLD 9–13 kPa suggestive of cACLD needs further testing 10 sample median; IQR/Median < 15% m/s, < 30% kPa. cACLD = compensated Advanced Chronic Liver Disease. This guide is based on meta-analysis and clinical studies using Siemens Healthineers Ultrasound. This guide is not intended to be used as a conversion table for liver stiffness readings to fibrosis stage or replace the performing physician’s judgment for the final diagnosis. † Mild: F ≥ 1: 1.18-1.19 m/s, F ≥ 2: 1.21-1.34 m/s, F ≥ 3: 1.54-1.61 m/s, F = 4: 1.80-2 m/s NAFLD: F ≥ 1: 1.10 m/s, F ≥ 2: 1.16 m/s, F ≥ 3: 1.48 m/s, F = 4: 1.63 m/s Sporea I., et al. Romanian National Guidelines and Practical Recommendations on Liver Elastography. Med Ultrasound. 2014, Vol 16, no2, 123-138. DOI:10.11152/mu.2013.2066.162.is1sb2 Significant/Severe/Cirrhosis: F ≥ 2: 1.34 m/s, F ≥ 3: 1.55 m/s, F = 4: 1.80 m/s Friedrich-Rust, M., et al. Performance of acoustic Radiation Force Impulse imaging for the staging of liver fibrosis: a pooled meta-analysis. Journal of Viral Hepatitis, 2012 doi:10.1111/j.1365-2893.2011.01537.x F ≥ 2: 1.30 m/s, F = 4: 1.80 m/s Bota S., et al. Meta-analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis. Liver International. 2013: 33: 1138-1147. DOI:10.1111/liv.12240 †† Society of Radiologists in Ultrasound (SRU): Barr R., et al. Update to the Society of Radiologists in Ultrasound Elastography Consensus Statement. Radiology. 2020; 296:263-274. https://doi.org/10.11.48/radiol.2020192437 SIEMENS Healthineers Rev: April 2021

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